With the advent of marijuana decriminalization and expanded use for medicinal purposes, the legal and human challenges regarding the opioid crisis also are expanding. One of the most challenging issues is knowing how and when to address an employee who appears to be struggling with an addiction issue. If the employer does choose to confront the employee, who denies addiction and refuses assistance, clear expectations for behavior and performance should be made clear. Other considerations include the return of an employee after rehab is completed, struggling family members and recreational or medicinal use of marijuana. Employers can prepare by enacting an employee assistance program (EAP), reviewing benefits offerings, updating policies and involving employees in community service or educational programs around mental health wellbeing.