Washington State University researchers, with Pulsar Informatics and the National Safety Council, conducted a pilot study examining how fatigue, alcohol, and cannabis affect alertness. Six male participants completed reaction time and driving tasks during extended wakefulness. Results showed sleep deprivation worsened attention and driving performance, while alcohol further slowed reactions and increased lapses. Cannabis increased lane deviation but not reaction time. Findings highlight how alcohol may amplify fatigue-related impairment in safety-sensitive work environments.

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